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KMID : 0361720100210040395
Korean Journal of perinatology
2010 Volume.21 No. 4 p.395 ~ p.402
Recent Outcomes of Very Low Birth Weight Infants of the Three University Hospital in the Busan Area
Kim Eun-Young

Jung Ji-Mi
Jung Yu-Jin
Kim Myo-Jing
Jeon Ga-Won
Hong Yoo-Rha
Sin Jong-Beom
Abstract
Objective : The survival rate of very low birth weight infants (VLBWI) has increased markedly in Korea. The purpose of this study was to investigate the outcome of VLBWI in Busan area.

Methods : We retrospectively reviewed 273 VLBWI less than 1,500 g who were admitted to the neonatal intensive care units of three university hospitals in Busan between January, 2007, to December, 2008. The survival rate, distribution of infants by birth weight and gestational age, and complications were compared with previous reports in Busan.

Results : We enrolled 273 VLBWI, including 31.1% extremely low birth weight infants, and the overall survival rate of VLBWI was 77.3%. Mean gestational age was 29.2¡¾2.9 weeks and birth weight was 1,115¡¾249 g. Infants weighing <750 g, 750-999 g, 1,000-1,249 g and 1,250-1,499 g showed survival rates of 30.4%, 62.9%, 83.0%, and 92.0%, respectively. Infants at ¡Â24 weeks, 25-26 weeks, 27-28 weeks and ¡Ã29 weeks had survival rates of 25.0%, 57.5%, 75.0%, and 91.0%, respectively. Survival rates by birth weight (<750 g, 750- 999 g) and gestational age (¡Â24 weeks, 25-26 weeks) had increased significantly compared to 2003-2005. Common morbidities of VLBWI included respiratory distress syndrome (54.9%), patent ductus arteriosus (33.3%), bronchopulmonary dysplasia (31.5%), sepsis (20.1%), necrotizing enterocolitis (7.3%), retinopathy of prematurity (¡Ã stage III) (6.2%) and intraventricular hemorrhage (¡ÃGr III) (5.1%).

Conclusions : The survival rate of VLBWI born in Busan was 77.3% over the past 2 years. Survival rates of extreme prematurity weighing less than 1,000g and gestational age of ¡Â26 weeks were significantly increased.
KEYWORD
Infant, Very low birth weight, Infant, Extremely low birth weight, Survival rate, Rrespiratory distress syndrome
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